Which of the following is not an effect of mitosis-promoting factor (MPF)involved in moving a cell into M phase?
A)phosphorylation of lamins,initiating breakdown of the nuclear membrane
B)phosphorylation of microtubule associated proteins,triggering the formation of the mitotic spindle
C)phosphorylation of an enzyme that breaks down the cyclin molecule
D)degradation of cyclin-dependent kinase

Question

Quizplus · Accepted Answer

Mitosis-promoting factor (MPF) is composed of cyclin and cyclin-dependent kinase (CDK). It leads to phosphorylation of lamins, breakdown of the nuclear membrane, phosphorylation of microtubule-associated proteins, and formation of the mitotic spindle. However, the degradation of cyclin-dependent kinase is not an effect of MPF. Instead, MPF itself is degraded through the action of an enzyme that breaks down the cyclin molecule. This degradation of MPF is necessary to exit from M phase and initiate the next cell cycle.

Which of the Following Is Not an Effect of Mitosis-Promoting