The M-phase checkpoint is designed to make sure all chromosomes are attached to the mitotic spindle.If this fails to happen,in which stage of mitosis would the cells be most likely to arrest?
A)telophase
B)prophase
C)prometaphase
D)metaphase

Question

Quizplus · Accepted Answer

The M-phase checkpoint monitors chromosome attachment to the mitotic spindle during metaphase. If all chromosomes are not properly aligned and attached to the spindle, the cell cycle will arrest at metaphase to prevent the formation of daughter cells with unequal chromosome content. Therefore, the cells are most likely to arrest in metaphase if the M-phase checkpoint fails.

The M-Phase Checkpoint Is Designed to Make Sure All Chromosomes