What is the expected result of a "nonsense" point mutation?
A)Total disruption of the gene reading frame, no production of protein
B)Replacement of one amino acid with another in the final gene product
C)Replacing an amino acid codon with a "stop" codon, resulting in a truncated protein product
D)No change in amino acid sequence and no change in the composition of the protein product

Question

Quizplus · Accepted Answer

A nonsense point mutation results in an inappropriate placement of a stop signal, which has a negative effect on protein function. This type of mutation prevents the completion of a protein. The protein may not be synthesized at all if the stop signal is present early in the reading sequence. If it is present later in the sequence, protein synthesis stops prematurely and results in a short or truncated protein that usually has little if any function.

What Is the Expected Result of a "Nonsense" Point Mutation