Why are people who have poor DNA repair mechanisms at greater risk for cancer development?
A)Their cancers are usually resistant to chemotherapy.
B)Their somatic mutations are more likely to be permanent.
C)They have greater exposure to environmental carcinogens.
D)They have sustained a mutational event in all cells and tissues.

Question

Quizplus · Accepted Answer

Everyone experiences some mutational events as a result of spontaneous DNA replication error or exposure to mutagens or carcinogens in the environment. Many of these mutational events are correctly repaired and have no lasting consequences. However, when they remain unrepaired and occur in a gene-coding region for cell growth regulation, they can have permanent consequences for the individual, including a greater risk for cancer development.

Why Are People Who Have Poor DNA Repair Mechanisms at Greater