Many integral membrane proteins have not been analyzed by X-ray crystallography.
However,transmembrane segments can be inferred using computer analysis of the amino
Acid sequence of the protein.This technique is known as
A)homeoviscous adaptation.
B)lipid analysis.
C)lipid rafting.
D)hydropathic analysis.
E)SDS-PAGE.

Question

Quizplus · Accepted Answer

The technique of inferring transmembrane segments using computer analysis of the amino acid sequence of the protein is known as hydropathic analysis. This method calculates the hydrophobicity of the amino acids in the sequence, and helps in predicting which stretches of the polypeptide chain are likely to be embedded in the hydrophobic lipid bilayer of the membrane. Options A, B, C, and E are not relevant to this technique.

Many Integral Membrane Proteins Have Not Been Analyzed by X-Ray