The Formation of Acetyl CoA Is Driven to Completion by

The formation of acetyl CoA is driven to completion by

A) the negative standard free energy for the first step of the reaction.
B) the negative standard free energy for the final step of the reaction.
C) removal of the product pyrophosphate by the enzyme pyrophosphatase.
D) the negative free energy for the formation of an ADP intermediate.
E) All of the above.