Which is an important intermediate in the production of bicarbonate ion from the metabolism of glutamine?

Question

Quizplus · Accepted Answer

The metabolism of glutamine produces α-ketoglutarate as an intermediate which can be converted to bicarbonate ion through several steps including the citric acid cycle and the activity of carbonic anhydrase. Glucose is not directly involved in this process, and while ammonia is produced from the breakdown of glutamine, it must be converted to ammonium ion before it can participate in bicarbonate ion production. Citrulline is not directly involved in glutamine metabolism.

Which Is an Important Intermediate in the Production of Bicarbonate