Periportal cells of the liver are nearest to the inflow of blood and have a higher capacity for urea synthesis than the perivenous cells that are near the outflow.

Question

Quizplus · Accepted Answer

This statement is true. Periportal cells, also known as hepatocytes, are located near the portal vein, which brings nutrient-rich blood from the digestive system to the liver. These cells have a higher density of both mitochondria and urea cycle enzymes, allowing for efficient urea synthesis. Perivenous cells, on the other hand, are located near the central vein, which drains blood from the liver to the vena cava. These cells have a lower density of urea cycle enzymes and are primarily involved in glycogen storage and fatty acid metabolism.

Periportal Cells of the Liver Are Nearest to the Inflow