Pepsin and trypsin are produced in the pancreas as zymogens.What might result if these two enzymes were not produced in the pancreas as zymogens,but as active pepsin and trypsin?
A)They would not be transported to the intestine because of their native charge.
B)They would not be folded properly by their chaperone molecules.
C)They would associate into inactive oligomeric forms.
D)They would begin to degrade and damage pancreatic proteins.

Question

Quizplus · Accepted Answer

If pepsin and trypsin were produced in the pancreas as active enzymes, they would start to degrade and damage the pancreatic proteins and tissues, leading to pancreatic inflammation and digestive disorders. Zymogens are inactive precursor forms of enzymes that can be safely transported to their target site and activated only when needed, thus preventing any accidental damage to the tissues.

Pepsin and Trypsin Are Produced in the Pancreas as Zymogens