Cells of the pancreas will incorporate radioactively labeled amino acids into proteins. This "tagging" of newly synthesized proteins enables a researcher to track their location. In this case, we are tracking an enzyme secreted by pancreatic cells. What is its most likely pathway?
A)ER → Golgi → nucleus
B)Golgi → ER → lysosome
C)nucleus → ER → Golgi
D)ER → Golgi → vesicles that fuse with plasma membrane
E)ER → lysosomes → vesicles that fuse with plasma membrane

Question

Quizplus · Accepted Answer

The most likely pathway for a secreted enzyme synthesized by pancreatic cells is ER → Golgi → vesicles that fuse with plasma membrane. This is because the enzyme needs to be transported out of the cell and therefore needs to go through the secretory pathway. The ER and Golgi are involved in protein modification and packaging, and the vesicles are responsible for transporting the protein to the plasma membrane for secretion.

Cells of the Pancreas Will Incorporate Radioactively Labeled Amino Acids