What is the mechanism in type IV hypersensitivity reactions?
A)Antibodies coat mast cells by binding to receptors that signal its degranulation followed by discharge of preformed mediators.
B)Antibodies bind to soluble antigens that were released into body fluids and the immune complexes are deposited in the tissues.
C)Cytotoxic T lymphocytes or lymphokine-producing Th1 cells attack and destroy cellular targets directly.
D)Antibodies bind to the antigen on the cell surface.

Question

Quizplus · Accepted Answer

Whereas types I, II, and III hypersensitivity reactions are mediated by antibody, type IV reactions are mediated by T lymphocytes and do not involve antibody . Type IV mechanisms occur through either cytotoxic T lymphocytes (Tc cells) or lymphokine-producing Th1 cells. Tc cells attack and destroy cellular targets directly.

What Is the Mechanism in Type IV Hypersensitivity Reactions