Which cells are the most responsible for the rejection of a transplanted organ, such as a heart?

Question

Quizplus · Accepted Answer

T cells are the most responsible for the rejection of a transplanted organ as they play a major role in the immune response against foreign tissues. They specifically target and destroy cells that display foreign antigens, which are markers on the surface of cells that indicate whether they belong to the body or not. B cells and eosinophils are involved in other aspects of the immune response, while macrophages may play a role in presenting foreign antigens to T cells, but ultimately it is the T cells that are the primary effector cells in organ rejection.

Which Cells Are the Most Responsible for the Rejection of a Transplanted