Graft-versus-host disease occurs in many marrow transplant patients because of the activity of

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Graft-versus-host disease (GVHD) is caused by the activation of donor T lymphocytes, which recognize the recipient's tissues as foreign and mount an immune response against them. This reaction can cause damage to the recipient's vital organs, leading to severe morbidity and mortality. GVHD is a major complication of allogeneic bone marrow transplantation, and efforts to prevent or treat GVHD are ongoing.

Graft-Versus-Host Disease Occurs in Many Marrow Transplant Patients Because of the Activity