Suppose that exposure to a chemical mutagen results in a change in the sequence that alters the 5' end of intron 1 (I₁). What might occur?
A) loss of the gene product
B) loss of E₁
C) premature stop to the mRNA
D) inclusion of I₁ in the mRNA
E) exclusion of E₂

Question

Quizplus · Accepted Answer

Altering the 5' end of Intron 1 could result in the inclusion of Intron 1 in the mRNA, which could lead to the expression of an aberrant or non-functional protein. This is because introns interrupt the coding sequence or exons, and their sequences are spliced out during mRNA processing. If an intron is not spliced out properly and is included in the mature mRNA molecule, it can cause a frameshift or nonsense mutation, leading to changes in the amino acid sequence or premature termination of translation.

Suppose That Exposure to a Chemical Mutagen Results in a Change