Use the following information to answer the next few questions.
Pharmacogenetics is an increasingly important discipline that uses genetic information to tailor the prescription of drug treatments to individuals. In the case of chemotherapy for breast cancer, for example, different patients need and/or respond to different treatments.
-Patients whose tumours are HER-2 positive respond to herceptin whereas other patients do not. Patients whose tumours have estrogen receptors will be best served if
A)their estrogen receptors are blocked by using RNAi.
B)their estrogen release is activated and/or elevated.
C)the estrogen receptors are blocked by other molecules that can use the same receptors.
D)they are given herceptin as well as estrogen.
E)they are given a complete hysterectomy.

Question

Quizplus · Accepted Answer

Patients whose tumours have estrogen receptors will be best served if the estrogen receptors are blocked by other molecules that can use the same receptors. This can be achieved through the prescription of drugs such as tamoxifen which acts as an estrogen receptor antagonist thereby blocking the receptor from binding with estrogen.

Use the Following Information to Answer the Next Few Questions