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In Most Individuals with Inherited Colon Cancer Susceptibility Who Do

Question 5

Multiple Choice

In most individuals with inherited colon cancer susceptibility who do not have excessive numbers of benign and premalignant polyps, the cancer susceptibility is caused by a heterozygous defect in a gene for:


A) Postreplication mismatch repair.
B) Genome-wide nucleotide excision repair.
C) The lipid phosphatase PTEN.
D) The antiapoptotic protein Bcl2.
E) The transcriptional regulator p53.

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