Which of the following acts as the chief regulator of iron absorption in the intestines?

Question

Quizplus · Accepted Answer

Hepcidin is a hormone that regulates iron absorption and acts as the chief regulator of iron absorption in the intestines. It inhibits the activity of ferroportin, a protein that transports iron out of enterocytes and into the bloodstream. This inhibition reduces the amount of iron that is absorbed from the diet. HFE is a protein that interacts with transferrin receptor-1 and is involved in regulating the uptake of iron from transferrin. Duodenal cytochrome-B reductase is an enzyme involved in the reduction of dietary iron in the duodenum. Ferroportin is a protein involved in the transport of iron out of enterocytes and into the bloodstream.

Which of the Following Acts as the Chief Regulator of Iron