A laboratory professsional reviewed the CBC of a patient who had a WBC count of 5 × 103/μL with 32% blasts present.Follow up testing with cytogenetics revealed t(15;17) ( q22;q12).Which of the following is a likely diagnosis for the patient?

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Quizplus · Accepted Answer

The presence of 32% blasts in the blood along with t(15;17) (q22;q12) suggests the likely diagnosis of acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML). MDS (myelodysplastic syndrome) typically presents with cytopenias and dysplastic changes in the bone marrow, while MPN (myeloproliferative neoplasms) and CLL (chronic lymphocytic leukemia) typically present with elevated WBC counts without blasts or with very low proportions of blasts.

A Laboratory Professsional Reviewed the CBC of a Patient Who