What is the screening test of choice in the workup of PNH?

Question

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The sugar-water test is the screening test of choice in the workup of PNH. This test is based on the fact that PNH red blood cells are more sensitive to lysis in acidified serum or isotonic sugar solutions. The test involves incubation of patient blood samples with acidified serum or sugar solution, and subsequent analysis for the presence of PNH red blood cells by flow cytometry or microscopy. If the sugar-water test is positive, a confirmatory test such as flow cytometry using CD55 and CD59 markers can be performed.

What Is the Screening Test of Choice in the Workup