A patient had the following results: RBC 2.45 × 10¹²/L MCV 90 fL
Hb 7.5 g/dL MCH 31 pg
Hct 22.0 % MCHC 34 g/dL
DAT negative
Haptoglobin 10 mg/dL
(Reference range: 35-164 for males and 40-175 for females)
Which is the most appropriate reflex test?

Question

Quizplus · Accepted Answer

The low RBC count, low Hb, and low Hct indicate anemia. To further investigate possible causes of anemia, a reticulocyte count should be done. The MCV and MCHC suggest a normocytic, normochromic anemia. Hemoglobin electrophoresis is typically done if there is suspicion of a hemoglobinopathy, but this is not suggested by the patient's results. Osmotic fragility test is used to evaluate the osmotic resistance of red blood cells, which is not relevant in this patient. Erythropoietin assay is used to evaluate erythropoietin production and is typically done in patients with primary erythrocytosis or to evaluate the response to therapy in patients with anemia.

A Patient Had the Following Results: RBC 2