The main disadvantage of the oral route of drug administration is
A) indigestion.
B) the binding of drugs to the wall of the stomach.
C) its relative unpredictability.
D) nausea.
E) that it promotes drug interactions.

Question

Quizplus · Accepted Answer

The main disadvantage of the oral route of drug administration is its relative unpredictability, as the drug must pass through the digestive system before entering the bloodstream. Factors such as food in the stomach or individual variations in the rate of absorption can affect the drug's effectiveness and make dosing less precise. Indigestion, binding to the stomach wall, nausea, and drug interactions can all be potential issues with the oral route, but they are not its primary disadvantage.

The Main Disadvantage of the Oral Route of Drug Administration