Biopsy tissue and cytology smears of early herpes simplex lesions show evidence of viral infection. The viral-induced changes would appear as alterations in the nuclei of which of the following cells?

Question

Quizplus · Accepted Answer

Herpes simplex virus primarily infects epithelial cells, leading to characteristic changes in their nuclei, such as ground-glass appearance, margination of chromatin, and formation of multinucleated giant cells. None of the options listed (Langerhans cells, inflammatory cells, fibroblasts, muscle cells) are the primary target for herpes simplex virus in early lesions.

Biopsy Tissue and Cytology Smears of Early Herpes Simplex Lesions