When should initiation of noninvasive ventilation be Considered in patients with Duchenne's muscular dystrophy
I.Forced vital capacity is less than 50% predicted.
II.Abnormal sleep study suggesting hypoventilation and hypercarbia
III.SpO₂ is less than 95% while awake.
IV.Maximal expiratory pressure is less than 40 cm H₂O.

Question

Quizplus · Accepted Answer

Noninvasive ventilation should be considered when there is evidence of ventilatory failure, which can be assessed by abnormal sleep study suggesting hypoventilation and hypercarbia (II) or SpO₂ is less than 95% while awake (III). Forced vital capacity less than 50% predicted (I) and maximal expiratory pressure less than 40 cm H₂O (IV) can also indicate respiratory muscle weakness, which may require noninvasive ventilation. Therefore, options I, II, and III are appropriate but option IV alone may not be sufficient to initiate noninvasive ventilation. The best choice among the given options is option C.

When Should Initiation of Noninvasive Ventilation Be Considered in Patients