All of the following molecules act as transcription factors in T cell activation signaling EXCEPT:
A)NF-B
B)Jun
C)Fos
D)NFAT
E)Ras

Question

Quizplus · Accepted Answer

All of the proteins listed are indeed involved in the activation of T cells, but Ras is not a transcription factor. NFAT, Jun, Fos, and NF- B are all transcription factors that play a role in T cell activation signaling. These transcription factors enter the nucleus and bind to DNA to regulate gene expression.
Ras, on the other hand, is a small GTPase that acts as a molecular switch in various signaling pathways, including those that lead to T cell activation. When Ras is bound to GTP, it is in an active state and can interact with and activate downstream effectors such as MAP kinases. These kinases then phosphorylate various targets, including transcription factors like Fos, which ultimately leads to changes in gene expression. However, Ras itself does not directly bind to DNA or function as a transcription factor; it is involved in signaling pathways that regulate the activity of transcription factors.

All of the Following Molecules Act as Transcription Factors in T