A patient's record indicated that he had a history of an antibody to HPA-1a.What is the significance of this antibody if this patient requires a platelet transfusion?
A)The patient would require HPA-1a negative platelets,which are relatively rare.
B)Transfusion of HLA-matched platelet donors would yield a better response.
C)Washed platelets are necessary to avoid antibody interference.
D)No testing is necessary because the frequency of HPA-1a positive donors is very rare.

Question

Quizplus · Accepted Answer

Anti-HPA-1a is a platelet antibody that would react with about 98% of the population,requiring the search for a relatively rare negative donor.In order for platelets to be successfully transfused,HPA-1a negative platelets should be transfused.

A Patient's Record Indicated That He Had a History of an Antibody