The difference between the minimal therapeutic and toxic concentrations of a drug is known as the

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The therapeutic index (TI)is the difference between the minimal therapeutic and toxic concentrations of a drug.The volume of distribution (V_D)is the ratio of the amount of drug administered versus the plasma concentration of the drug.For an aerosol drug (bronchodilator,corticosteroid,mediator antagonist)that targets the respiratory tract,the L/T ratio is defined as the proportion of drug available from the lung out of the total systemically available drug.Plasma half-life (T_1/2)describes the amount of time required for the plasma concentration of a drug to decrease by one-half.

The Difference Between the Minimal Therapeutic and Toxic Concentrations of a Drug