An allergic or immune-mediated reaction to a drug,which can be serious,requiring airway maintenance or ventilatory assistance is called

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Hypersensitivity describes an allergic or immune-mediated response to a drug,which can be serious,requiring airway maintenance or ventilatory assistance.Potency refers to the concentration (EC₅₀)or dose (ED₅₀)of a drug producing 50% of the maximal response of the drug.Additivity occurs when two drugs act on the same receptors and the combined effect is the simple linear sum of the effects of the two drugs,up to a maximal effect.Potentiation is a special case of synergism in which one drug has no effect but can increase the activity of another drug.

An Allergic or Immune-Mediated Reaction to a Drug,which Can Be