Osmotic diuretics function by

Question

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Osmotic diuretics are freely filtered at the glomerulus but are not reabsorbed.These agents remain in the tubule lumen and impair the ability of the proximal tubule and thick ascending limb of the loop of Henle to reabsorb NaCl.The net result is that osmotic substances are potent diuretics that lead to increased excretion of water and NaCl.However,the resultant increased delivery of sodium and chloride to the distal tubule results in increased exchange of Na⁺ for K⁺,producing a net K⁺ loss in urine.

Osmotic Diuretics Function by