Which of the following tests would help differentiate between MDS/MPD disorders and CML?

Question

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Cytogenetic analysis is the best choice to differentiate between MDS/MPD disorders and CML. In MDS/MPD disorders, there may be chromosome abnormalities, but in CML, there is a specific translocation between chromosomes 9 and 22 called the Philadelphia chromosome. CBC, PB smear, and LAP stain may be useful in identifying abnormal cells, but they are not specific enough to diagnose the specific disorder.

Which of the Following Tests Would Help Differentiate Between MDS/MPD