A panel of cytochemical stains is performed to determine a patient's subtype of AML. Myeloperoxidase and Sudan Black B are positive. Specific esterase is positive and nonspecific esterase o is negative. Based on this information, what lineage is implicated as the chosen subtype of AML?

Question

Quizplus · Accepted Answer

Myeloperoxidase and Sudan Black B stains are positive in myeloid lineage. Specific esterase can also be positive in myeloid lineage, whereas nonspecific esterase o is typically negative in myeloid lineage. Therefore, this patient's AML subtype is most likely of myeloid origin.

A Panel of Cytochemical Stains Is Performed to Determine a Patient's