The expression of several antigens from two different lineages complicates the placement of the diagnosis into categories of AML and ALL.This biphenotypic expression toward more than one lineage restricts the use of immunophenotyping.In differentiating AML and ALL, staining with which of the following cytochemical stains indicates AML?

Question

Quizplus · Accepted Answer

Myeloperoxidase staining is specific for myeloid lineage and is commonly used in differentiating AML from ALL. PAS staining is used to detect glycogen and mucopolysaccharides, Giemsa staining is used for morphological assessment, and Thiazole orange staining is used to detect DNA content and cell viability.

The Expression of Several Antigens from Two Different Lineages Complicates