The major pathologic or structural changes associated with cystic fibrosis include:
1) partial airway obstruction leading to hyperinflation.
2) bronchospasm.
3) thick, tenacious mucus.
4) total airway obstruction leading to atelectasis.

Question

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Patients with cystic fibrosis have thick, tenacious mucus. This can lead to either a partial airway obstruction (and hyperinflation) or total airway obstruction (and atelectasis). Bronchospasm is only occasionally found.

The Major Pathologic or Structural Changes Associated with Cystic Fibrosis