Which of the Following Can Stimulate an Increased Respiratory Rate

Which of the following can stimulate an increased respiratory rate when a flail chest is present?
1) Activation of deflation receptors
2) Activation of irritant receptors
3) Stimulation of J receptors
4) Pain and anxiety

A) 1, 3
B) 1, 4
C) 1, 2, 3
D) 1, 2, 3, 4