How do protein kinases generally activate their target proteins?
A)The process of phosphorylation causes the target to change conformation.
B)The kinases bind to target proteins directly,forming a complex that activates the protein and lets them change conformations.
C)Kinases vary their concentrations through the cell cycle,so that proteins are activated only when kinase levels are high.
D)Kinases bind to target proteins and inactivate them,so kinase levels must drop for target protein activation.
E)The process of dephosphorylation causes the target to change conformations.

Question

Quizplus · Accepted Answer

Protein kinases activate their target proteins by adding a phosphate group to a specific amino acid residue via a process called phosphorylation. This adds a negative charge to the target protein, which can cause a conformational change, exposing binding sites or inducing interactions with other proteins within the cell. Therefore, choice A is the correct answer.

How Do Protein Kinases Generally Activate Their Target Proteins