Which of the Following Is (Are) Precipitating Factor(s) That Can

Which of the following is (are) precipitating factor(s) that can decrease the patient's ability to generate a negative intrapleural pressure?
1) Supine position
2) Large tidal volume on the mechanical ventilator
3) Malnutrition
4) Obesity

A) 4
B) 1, 3, 4
C) 1, 2, 3
D) 1, 2, 3, 4