Which of the Following Is a Feature of Energy Intake

Which of the following is a feature of energy intake and longevity?

A) Improvements in longevity with energy restriction depend on reducing energy intake but not on the amount of body fat
B) Restriction of energy intake in genetically obese animals does not seem to improve longevity
C) Biochemical markers for longevity in humans are improved only when energy intake is reduced by at least one-third
D) The activities of the genes of older mice on energy-restricted diets are similar to those of mice on standard diets
E) Research with humans has found a substantial increase in longevity with a 5% reduction in energy intake