The primary pathogenic effect of increased Shiga toxins within cells is:

Question

Quizplus · Accepted Answer

The primary pathogenic effect of increased Shiga toxins is inhibition of protein synthesis, specifically by targeting the 60S ribosomal subunit. This can lead to cell death, organ damage, and systemic effects such as hemolytic uremic syndrome. Loss of cellular energy, increased ADP synthesis, disruptions of ion and water balance, and overactivity of ATP synthase are not the primary effects of Shiga toxins.

The Primary Pathogenic Effect of Increased Shiga Toxins Within Cells