A family pedigree is used to determine whether a disease has a genetic component.The proband can be defined as:

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For nurses,it is important to ask questions that elucidate which family members are affected versus those who are unaffected and then to identify the individuals who may carry the gene in question but who do not have symptoms (carriers).The proband is the name given to the first person diagnosed in the family pedigree.Homozygous versus heterozygous determines if the disorder is carried by a gene from one or both parents.The xy band determines if the disorder is carried through the sex genes.A disease locus is the genetic address of the disorder.

A Family Pedigree Is Used to Determine Whether a Disease