When both parents have sickle cell trait, which is the chance their children will have sickle cell anemia?
A) 25%
B) 50%
C) 75%
D) 100%

Question

Quizplus · Accepted Answer

Sickle cell anemia is inherited in an autosomal recessive pattern. If both parents have sickle cell trait (one copy of the sickle cell gene), then for each pregnancy, a 25% chance exists that their child will be affected with sickle cell disease. With each pregnancy, a 50% chance exists that the child will have sickle cell trait. Percentages of 75% and 100% are too high for the children of parents who have sickle cell trait.

When Both Parents Have Sickle Cell Trait, Which Is the Chance