Which of the following patterns of markers is a normal immune response after recovery from a hepatitis B viral (HBV)infection?
A)Negative hepatitis B surface antigen (HBsAg);negative hepatitis B core antibody (anti-HBcAb);and negative hepatitis B surface antibody (anti-HBsAb)
B)Positive HBsAg;negative anti-HBcAb;and negative anti-HBsAb
C)Positive HBsAg;positive HBeAg (hepatitis Be antigen);and negative anti-HBsAb
D)Negative HBsAg;positive anti-HBcAb;and positive anti-HBsAb

Question

Quizplus · Accepted Answer

HBsAg is the most reliable marker for the identification of an HBV infection.The antigen becomes evident in the patient's serum weeks before any biochemical evidence associated with liver damage is observed.(Biochemical liver assays may show only minimal elevation. )HBsAg remains in the serum during the acute and chronic stages of HBV.The presence of HBsAg 6 months after acute infection indicates that the patient is a chronic carrier.Immunoglobulin M (IgM)anti-HBcAb to hepatitis B core antigen (HBcAg)appears early in the course of disease during the acute infection.Anti-HBsAg indicates the patient is in convalescence and has developed immunity.Finally,the presence of the extracellular form of HBcAg (HBeAg)indicates high infectivity and a chronic carrier state.

Which of the Following Patterns of Markers Is a Normal