What is the explanation for the relatively high frequency of rare autosomal recessive disorders in the Old Order Amish population?

Question

Quizplus · Accepted Answer

The relatively high frequency of rare autosomal recessive disorders in the Old Order Amish population is attributed to the Founder effect. Due to the small founding population size and subsequent genetic isolation, rare alleles become more frequent in the population through genetic drift. This can lead to a higher frequency of diseases caused by recessive alleles if the rare allele happens to be disease-causing.

What Is the Explanation for the Relatively High Frequency of Rare