To Search for Loci Involved in Autosomal Recessive Diseases,which Alternative

To search for loci involved in autosomal recessive diseases,which alternative approach to a traditional linkage analysis can be used?

A) Look for shared alleles between affected families
B) Look for shared regions of deletion between affected families
C) Look for regions of homozygosity in affected families
D) Look for uniparental heterodisomy
E) Look for uniparental homodisomy