Intestinal polyps seen with Peutz-Jeghers syndrome are

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Intestinal polyps seen with Peutz-Jeghers syndrome are hamartomas. Intestinal polyps seen with Peutz-Jeghers syndrome develop mostly in the small intestine; only rarely do they undergo malignant transformation. Gardner syndrome is associated with inevitable malignant transformation of intestinal polyps into adenocarcinomas. The adenomatous polyposis coli (APC) gene responsible for Gardner syndrome is located on the long arm of chromosome 5. One of the basic components of Gardner syndrome is the presence of osteomas in various bones, especially the frontal bones, mandible, and maxilla.

Intestinal Polyps Seen with Peutz-Jeghers Syndrome Are