Question 1

"Keratin pearls" are a characteristic feature of

Accepted Answer

"Keratin pearls" are a characteristic feature of squamous cell carcinoma. Well-differentiated tumors show keratin formation because keratin is a product of squamous epithelium. The neoplastic cells contain large hyperchromatic nuclei and numerous mitotic figures. Some of the mitotic figures appear normal, whereas others are bizarre. "Keratin pearls" are a characteristic feature of squamous cell carcinoma and not basal cell carcinoma. "Keratin pearls" are a characteristic feature of squamous cell carcinoma and not pleomorphic adenoma. "Keratin pearls" are a characteristic feature of squamous cell carcinoma and not monomorphic adenoma.

Question 2

Squamous cell carcinoma of the oral epithelium usually metastasizes first to which site?

Accepted Answer

Squamous cell carcinoma of the oral epithelium usually metastasizes first to the lymph nodes of the neck. From there, it proceeds to more distant sites such as the lungs and liver. Squamous cell carcinoma of the oral epithelium usually metastasizes first to the lymph nodes of the neck rather than the spleen.

Question 3

Which statement about erythroplakia is true?

Accepted Answer

When examined microscopically, 90% of cases of erythroplakia demonstrate epithelial dysplasia or squamous cell carcinoma. Most cases of erythroplakia occur in the floor of the mouth, tongue, and soft palate. Erythroplakia is much less common than leukoplakia. Erythroplakia is considered a more serious clinical finding than leukoplakia. A biopsy must be performed to establish a definitive diagnosis.

Question 4

Which statement about epithelial dysplasia is true?

Accepted Answer

Unlike squamous cell carcinoma, cellular changes in epithelial dysplasia may revert to normal if the stimulus, such as tobacco smoking, is removed. Epithelial dysplasia is considered a premalignant condition. Epithelial dysplasia may present clinically as an erythematous lesion, as a white lesion, or as a mixed erythematous and white lesion. Epithelial dysplasia lesions often arise in the floor of the mouth or tongue.

Question 5

Where do most cases of papilloma occur?

Accepted Answer

Most cases of papilloma occur on the soft palate or tongue. The papilloma is a benign tumor that presents as a small, exophytic, pedunculated, or sessile growth. These tumors are composed of numerous papillary projections that may either be white or the color of normal mucosa. The more keratin, the whiter the lesion appears clinically. Most cases of papilloma occur on the soft palate or tongue rather than the hard palate. Most cases of papilloma occur on the soft palate or tongue rather than the buccal mucosa. Most cases of papilloma occur on the soft palate or tongue rather than the retromolar area.

Question 6

As a general rule, a patient should be referred to an oral and maxillofacial surgeon or dermatologist to have a biopsy performed on any non healing ulcer of the skin or lips that has been present for more than

Accepted Answer

As a general rule, a patient should be referred to an oral and maxillofacial surgeon or dermatologist to have a biopsy performed on any non healing ulcer of the skin or lips that has been present for more than 10 days. A biopsy should be performed on any non healing ulcer of the skin or lips that has been present for more than 10 days, not 24 hours. A biopsy should be performed on any non healing ulcer of the skin or lips that has been present for more than 10 days, not 3 months. A biopsy should be performed on any non healing ulcer of the skin or lips that has been present for more than 10 days, not 1 year.

Question 7

Which choice represents a characteristic of malignant tumors?

Accepted Answer

Malignant tumors have the ability to spread to distant sites. Cancer is synonymous with malignancy. Encapsulated is a characteristic of benign rather than malignant tumors. It means the tumor is walled off by surrounding fibrous connective tissue. Sometimes a benign tumor can invade adjacent structures, but it does not have the ability to spread to distant sites. The cells of benign tumors almost always resemble normal cells, whereas malignant tumors vary in their histologic appearance.

Question 8

Most cases of verrucous carcinoma occur in the _____ years old.

Accepted Answer

Most cases of verrucous carcinoma occur in the vestibule and buccal mucosa of men over 55 years old. Most cases of verrucous carcinoma occur in the vestibule and buccal mucosa of men over 55 years old rather than on the posterior lateral border of the tongue of women over 40 years old. Most cases of verrucous carcinoma occur in the vestibule and buccal mucosa of men over 55 years old rather than on the floor of the mouth of women over 70 years old. Most cases of verrucous carcinoma occur in the vestibule and buccal mucosa of men over 55 years old rather than in the bone of the mandible of men over 20 years old.

Question 9

A papilloma is a _____ tumor derived from _____ epithelium.

Accepted Answer

A papilloma is a benign tumor derived from squamous epithelium. Three different types of epithelial tumors occur in the oral cavity: tumors derived from squamous epithelium, tumors derived from salivary gland epithelium, and tumors derived from odontogenic epithelium. A papilloma is a benign tumor derived from squamous rather than salivary gland epithelium. An adenoma is a benign tumor derived from salivary gland epithelium. A papilloma is a benign rather than malignant tumor derived from squamous epithelium. A squamous cell carcinoma is a malignant tumor derived from squamous epithelium. A papilloma is a benign tumor derived from squamous epithelium rather than a malignant tumor derived from odontogenic epithelium.

Question 10

Anaplastic means the tumor

Accepted Answer

Anaplastic means the tumor does not resemble the tissue from which it was derived. Pleomorphic means the tumor is composed of cells that vary in size and shape. The nuclei of malignant tumor cells are often hyperchromatic; that is, they are darker than those of normal cells. The nuclei of malignant tumor cells exhibit an increased nuclear-to-cytoplasmic ratio, but anaplastic means the tumor does not resemble the tissue from which it was derived.

Question 11

According to the TNM staging system for oral squamous carcinoma, T₂, N₁, M₀ would mean tumor _____ cm in diameter, _____ palpable nodes, and _____ metastasis.

Accepted Answer

According to the TNM staging system for oral squamous carcinoma, T₂, N₁, M₀ would mean tumor 2 to 4 cm in diameter, ipsilateral palpable nodes, and no distant metastasis. According to the TNM staging system for oral squamous carcinoma, T₁, N₁, M₀ would mean tumor less than 2 cm in diameter, ipsilateral palpable nodes, and no distant metastasis. According to the TNM staging system for oral squamous carcinoma, T₂, N₂, M₀ would mean tumor 2 to 4 cm in diameter, contralateral palpable nodes, and no distant metastasis. According to the TNM staging system for oral squamous carcinoma, T₂, N₂, M₁ would mean tumor 2 to 4 cm in diameter, contralateral palpable nodes, and distant metastasis.

Question 12

Idiopathic leukoplakia

Accepted Answer

Idiopathic leukoplakia does not have a specific known cause. Idiopathic leukoplakia is considered a premalignant rather than malignant lesion. Leukoplakia cannot be rubbed off and cannot be diagnosed as a specific disease. Most leukoplakias are the result of hyperkeratosis or a combination of epithelial hyperplasia and hyperkeratosis. Idiopathic leukoplakia does not have a specific known cause.

Question 13

Which choice is not regarded as an initiating factor in the development of oral cancer?

Accepted Answer

No evidence exists that chronic irritation is an initiating factor in the development of oral cancer. The most significant risk factor associated with the development of squamous cell carcinoma is tobacco use, including cigar, pipe, and cigarette smoking, snuff dipping, and tobacco chewing. Alcohol consumption appears to add to the risk of oral squamous cell carcinoma, especially in individuals who also use tobacco products.

Question 14

Verrucous carcinoma

Accepted Answer

Verrucous carcinoma has a better prognosis than other forms of squamous cell carcinomas. Verrucous carcinoma appears clinically as a slow-growing exophytic tumor with a pebbly white and red surface. Verrucous carcinoma is characterized by well-differentiated epithelium, does not contain atypical cells, and exhibits broad-based rete pegs that penetrate deeply into the connective tissue. The epithelial basement membrane is intact in cases of verrucous carcinoma, and the tumor does not show invasion of tumor cells through the basement membrane, as is seen in squamous cell carcinoma.

Question 15

An intraoral mucosal lesion that shows a mixture of red and white areas is termed

Accepted Answer

An intraoral mucosal lesion that shows a mixture of red and white areas is generally called speckled leukoplakia. An intraoral mucosal lesion that shows a mixture of red and white areas is generally called speckled leukoplakia rather than erythroplakia. An intraoral mucosal lesion that shows a mixture of red and white areas is generally called speckled leukoplakia rather than speckled erythroplakia. An intraoral mucosal lesion that shows a mixture of red and white areas is generally called speckled leukoplakia rather than simply leukoplakia.

Question 16

Basal cell carcinoma is a _____ tumor that _____ in the oral cavity.

Accepted Answer

Basal cell carcinoma is a malignant tumor that does not occur in the oral cavity. It is associated with excessive exposure to the sun. It frequently arises on the skin of the face and appears as a non healing ulcer with characteristic rolled borders. Basal cell carcinoma is a malignant tumor, not a benign tumor, and does not occur in the oral cavity.

Question 17

Squamous cell carcinomas on the vermilion border of the lips and skin of the face are

Accepted Answer

Squamous cell carcinomas on the vermilion border of the lips and skin of the face are associated with color changes of the vermilion border from dark pink and uniform to mottled grayish-pink. Squamous cell carcinomas are associated with exposure to the sun. Squamous cell carcinomas tend to be more common in individuals with fair skin. Squamous cell carcinomas of the lips and skin are associated with a much better prognosis than that for squamous cell carcinomas of the oral mucosa.

Question 18

A benign tumor of bone is called a(n)

Accepted Answer

A benign tumor of bone is called an osteoma. The prefix of the name of a tumor is determined by the tissue or cell of origin. The suffix -oma is used to indicate a tumor. Malignant tumors of epithelium are called carcinomas, and malignant tumors of connective tissue are called sarcomas. Thus a malignant tumor of bone is an osteogenic sarcoma. A chondroma is a benign tumor of cartilage. A carcinoma is a malignant tumor of epithelium.

Question 19

Severe epithelial dysplasia involving the full thickness of the epithelium is termed

Accepted Answer

Severe epithelial dysplasia involving the full thickness of the epithelium is called carcinoma in situ. Anaplasia is characterized by a loss of differentiation of cells and their orientation to one another. Squamous cell carcinoma is a malignant tumor of squamous epithelium. Metastasis means that neoplastic cells are transported to parts of the body remote from the primary tumor and that new tumors are established at those sites.

Question 20

Intraoral minor salivary gland tumors are most commonly located

Accepted Answer

Intraoral minor salivary gland tumors are most commonly located at the junction of the hard and soft palate. They can also occur on the labial and buccal mucosa, the retromolar area, the floor of the mouth, and rarely the tongue. Tumors of minor salivary gland origin are much more common in the upper lip than in the lower lip.

Quiz 7: Neoplasia

"Keratin pearls" are a characteristic feature of

Squamous cell carcinoma of the oral epithelium usually metastasizes first to which site?

Which statement about erythroplakia is true?

Which statement about epithelial dysplasia is true?

Where do most cases of papilloma occur?

As a general rule, a patient should be referred to an oral and maxillofacial surgeon or dermatologist to have a biopsy performed on any non healing ulcer of the skin or lips that has been present for more than

Which choice represents a characteristic of malignant tumors?

Most cases of verrucous carcinoma occur in the _____ years old.

A papilloma is a _ tumor derived from _ epithelium.

Anaplastic means the tumor

According to the TNM staging system for oral squamous carcinoma, T₂, N₁, M₀ would mean tumor ___ cm in diameter, _ palpable nodes, and ___ metastasis.

Idiopathic leukoplakia

Which choice is not regarded as an initiating factor in the development of oral cancer?

Verrucous carcinoma

An intraoral mucosal lesion that shows a mixture of red and white areas is termed

Basal cell carcinoma is a _ tumor that _ in the oral cavity.

Squamous cell carcinomas on the vermilion border of the lips and skin of the face are

A benign tumor of bone is called a(n)

Severe epithelial dysplasia involving the full thickness of the epithelium is termed

Intraoral minor salivary gland tumors are most commonly located

Quiz 7: Neoplasia

"Keratin pearls" are a characteristic feature of

Squamous cell carcinoma of the oral epithelium usually metastasizes first to which site?

Which statement about erythroplakia is true?

Which statement about epithelial dysplasia is true?

Where do most cases of papilloma occur?

As a general rule, a patient should be referred to an oral and maxillofacial surgeon or dermatologist to have a biopsy performed on any non healing ulcer of the skin or lips that has been present for more than

Which choice represents a characteristic of malignant tumors?

Most cases of verrucous carcinoma occur in the _____ years old.

A papilloma is a _____ tumor derived from _____ epithelium.

Anaplastic means the tumor

According to the TNM staging system for oral squamous carcinoma, T2, N1, M0 would mean tumor _____ cm in diameter, _____ palpable nodes, and _____ metastasis.

Idiopathic leukoplakia

Which choice is not regarded as an initiating factor in the development of oral cancer?

Verrucous carcinoma

An intraoral mucosal lesion that shows a mixture of red and white areas is termed

Basal cell carcinoma is a _____ tumor that _____ in the oral cavity.

Squamous cell carcinomas on the vermilion border of the lips and skin of the face are

A benign tumor of bone is called a(n)

Severe epithelial dysplasia involving the full thickness of the epithelium is termed

Intraoral minor salivary gland tumors are most commonly located

A papilloma is a _ tumor derived from _ epithelium.

According to the TNM staging system for oral squamous carcinoma, T₂, N₁, M₀ would mean tumor ___ cm in diameter, _ palpable nodes, and ___ metastasis.

Basal cell carcinoma is a _ tumor that _ in the oral cavity.