Anaplastic means the tumor

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Anaplastic means the tumor does not resemble the tissue from which it was derived. Pleomorphic means the tumor is composed of cells that vary in size and shape. The nuclei of malignant tumor cells are often hyperchromatic; that is, they are darker than those of normal cells. The nuclei of malignant tumor cells exhibit an increased nuclear-to-cytoplasmic ratio, but anaplastic means the tumor does not resemble the tissue from which it was derived.

Anaplastic Means the Tumor