The major primary threat to a person with acquired immune deficiency syndrome (AIDS) is:

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AIDS weakens the immune system, making the person susceptible to infections. These infections can be life-threatening and range from opportunistic infections (infections that take advantage of the weakened immune system) to common infections that can become more severe in people with AIDS. While weight loss and organ damage can be consequences of AIDS, the primary threat is infection. Heart failure is not directly related to AIDS.

The Major Primary Threat to a Person with Acquired Immune