What Is the Consequence of a Deleterious Mutation Becoming Fixed

What is the consequence of a deleterious mutation becoming fixed in a population?

A) Muller's ratchet will automatically move an additional turn.
B) Recombination cannot remove the mutation.
C) Mating between unrelated individuals can produce offspring that do not carry the mutation.
D) Muller's ratchet may move an additional turn.
E) B and D