For a 40-Year-Old, 75-Kg Man, Drug X Has a Volume

For a 40-year-old, 75-kg man, drug X has a volume of distribution of 40 L and a clearance of 25 ml/min. Calculate the predicted loading dose of drug X to achieve a plasma concentration of 2 μg/ml.

A) 20 μg
B) 80 μg
C) 20 mg
D) 50 mg
E) 80 mg