Which of the following substances prevents the release of Ca²⁺ from the sarcoplasmic reticulum?

Question

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In the body,the process of smooth muscle relaxation uses cyclic guanosine monophosphate (cGMP)to reduce Ca²⁺ levels.In smooth muscle cells cGMP activates cGMP-dependent kinase,preventing the release of Ca²⁺ from the sarcoplasmic reticulum,resulting in smooth muscle relaxation.In the early 1980s researchers reported a potent smooth muscle-relaxing agent,endothelium-derived relaxing factor (EDRF),now understood to be endogenous nitric oxide.

Which of the Following Substances Prevents the Release of Ca²⁺