Inhaled NO Has Been Administered to an Infant for Nearly

Inhaled NO has been administered to an infant for nearly 4 hours.The respiratory therapist notices suboptimal response and suggests HFOV.What is the principle behind the potential benefit of adding this ventilatory modality to this infant?

A) HFOV improves ventilation and reduces the formation of NO₂.
B) Lung volumes are optimized with HFOV and further enhance the effects of iNO.
C) The high frequency accelerates the diffusion of NO through the alveolar surface.
D) HFOV reduces the need for higher doses of iNO.